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Some blood tests used to diagnose cancer include:
A test to count your blood cells. A complete blood count (CBC) measures the amount of each type of blood cell in a sample of your blood. Blood cancers may be found using this test.
A test that looks at the blood proteins. An electrophoresis blood test looks at the various proteins in your blood to find the ones made by your body's germ-fighting immune system. This test is helpful in diagnosing multiple myeloma.
Tests to find chemicals made by cancer cells. Tumor marker tests use a sample of blood to look for chemicals made by cancer cells.
These tests don't always help with diagnosing cancer because many healthy cells also make these chemicals. And some conditions that aren't cancer can cause high levels of tumor markers. Instead, tumor marker tests are mostly used after your cancer diagnosis to see if treatment is working.
Examples of tumor markers include prostate-specific antigen (PSA) for prostate cancer and cancer antigen 125 (CA 125) for ovarian cancer. Other examples include carcinoembryonic antigen (CEA) for colon cancer and alpha-fetoprotein for testicular cancer.
Table 1 Evolution of peripheral blood cell counts during therapy
Full size table
Fig. 3
A--FISH study on day 33 of treatment, B--RT-PCR test on day 33 of treatment. Lane 1: size marker; lane 2: positive control; lane 3: patient; lane 4: negative control, lane 5: internal reference gene--ABL1
Due to the general condition of the patient, consolidation treatment was delayed by 25 days. After this time, according to the EsPhALL 2009 protocol the IB protocol was started and Imatinib was resumed. Another PCR-MRD test was performed on day 17 of treatment (TP1b) of the IB protocol. PCR-MRD in TP1b was negative. Therefore the patient continued chemotherapy without qualification for HSCT (Hematopoietic Stem Cell Transplantation). The patient after consolidation therapy was in haematological remission of ALL. The patient remains without a transplant for 8 months after diagnosis.