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Increased nuchal translucency and subcutaneous edema In a recent series from our group, comprising 104 cases of nuchal or subcutaneous edema and fetal hydrops diagnosed in early pregnancy (unpublished data), the condition resolved in approximately 80% of the cases by the time of the 11-14-week scan. However, the incidence of chromosomal abnormalities and major structural defects in this group was 21.5%, necessitating detailed sonographic examination at 11-14 weeks and changing the screening or diagnostic pathway in many cases. This high rate of adverse pregnancy outcome in cases of early subcutaneous edema is similar to that reported by Votino et al.8. Figure 5 shows cases of nuchal and generalized subcutaneous edema at 10 weeks of gestation.

Increased nuchal translucency and subcutaneous edema In a recent series from our group, comprising 104 cases of nuchal or subcutaneous edema and fetal hydrops diagnosed in early pregnancy (unpublished data), the condition resolved in approximately 80% of the cases by the time of the 11-14-week scan. However, the incidence of chromosomal abnormalities and major structural defects in this group was 21.5%, necessitating detailed sonographic examination at 11-14 weeks and changing the screening or diagnostic pathway in many cases. This high rate of adverse pregnancy outcome in cases of early subcutaneous edema is similar to that reported by Votino et al.8. Figure 5 shows cases of nuchal and generalized subcutaneous edema at 10 weeks of gestation.